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Item number: Cay18006-1

Bone morphogenetic proteins (BMPs) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. Activation of BMP type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the...

Keywords:	1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]-piperazine
Application:	ALK2 inhibitor
CAS	1627503-67-6
MW:	419.5 D

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LDN-214117

Item number: TGM-T1944-100mg

Description: LDN-214117 is a potent and selective ALK2 inhibitor. Target: ALK, TGF-beta/Smad. Smiles: COc1cc(cc(OC)c1OC)-c1cc(cnc1C)-c1ccc(cc1)N1CCNCC1. References: Mohedas AH, et al. J Med Chem. 2014, 57(19), 7900-7915.

Application:	ALK2 inhibitor
CAS	1627503-67-6
MW:	419.52 D

From 32.00€ *

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