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AZD8186
AZD8186

Item number: TGM-T6773-100mg

Description: AZD8186 is an effective and specific PI3Kbeta/delta inhibitor (IC50: 4/12 nM). Target: PI3K. Smiles: C[C@@H](Nc1cc(F)cc(F)c1)c1cc(cc2c1oc(cc2=O)N1CCOCC1)C(=O)N(C)C. References: Barlaam B, et al. J Med Chem. 2015, 58(2), 943-962.
Application: PI3Kbeta/delta inhibitor
CAS 1627494-13-6
MW: 457.47 D
From 40.00€ *
Review
AZD 8186
AZD 8186

Item number: Cay17384-1

AZD 8186 is a selective PI3Kbeta/delta inhibitor that exhibits IC50 values of 3, 17, and 752 nM for PI3Kbeta, delta, and alpha, respectively, in cells sensitive to isoform-specific PI3K inhibition. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 µM and...
Keywords: 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-6-carboxamide
Application: PI3Kbeta/delta inhibitor
CAS 1627494-13-6
MW: 457.5 D
From 44.00€ *
Review
AZD-8186
AZD-8186

Item number: LKT-A985132.100

Selective inhibitor of PI3Kbeta and PI3Kdelta.
Keywords: AZD 8186, AZD8186
Application: PI3Kbeta/delta inhibitor
CAS 1627494-13-6
MW: 457.48 D
From 104.00€ *
Review