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Item number: Cay16066-1

Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin...

Keywords:	4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, monohydrobromide
Application:	NAT10 inhibitor
CAS	1622921-15-6
MW:	363.3 D

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Remodelin hydrobromide

Item number: TGM-T6133-100mg

Description: Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. Target: Histone Acetyltransferase, RAAS. Smiles: C1CCC(=NNc2nc(cs2)c2ccc(cc2)C#N)C1.Br. References: Larrieu D, et al. Science. 2014, 344(6183), 527-532.

Keywords:	Remodelin HBR, Remodelin
Application:	NAT10 inhibitor
CAS	1622921-15-6
MW:	363.28 D

From 49.00€ *

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