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Item number: Cay20308-1

GSK481 is an inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIP1 or RIPK1) that blocks autophosphorylation of Ser166 on wild-type human RIP1 with an IC50 value of 2.8 nM. It is selective for RIP1 over a panel of over 450 other kinases, including RIP3. GSK481 inhibits RIP1 from human and...

Keywords:	5-(phenylmethyl)-N-[(3S)-2,3,4,5-tetrahydro-5-methyl-4-oxo-1,5-benzoxazepin-3-yl]-3-isoxazolecarboxamide
Application:	RIP1 Ser166 phosphorylation inhibitor
CAS	1622849-58-4
MW:	377.4 D

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