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KY-226
KY-226

Item number: Cay43555-10

KY-266 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B, IC50 = 0. µM). It enhances insulin-induced phosphorylation of insulin receptors in HepG2 cells when used at concentrations of 1, 3, and 10 µM. In vivo, KY-266 (10 and 30 mg/kg) reduces plasma glucose and triglyceride levels and hemoglobin A1c (HbA1c)...
Keywords: 4-[[([1,1'-biphenyl]-4-ylmethyl)thio]methyl]-N-(hexylsulfonyl)-benzamide
Application: PTP1B inhibitor
CAS 1621673-53-7
MW: 481.67 D
From 91.00€ *
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KY-226
KY-226

Item number: TGM-T7704-100mg

Description: KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 µM,). Target: Phosphatase. Smiles: CCCCCCS(=O)(=O)NC(=O)c1ccc(CSCc2ccc(cc2)-c2ccccc2)cc1. References: Ito Y , Fukui M , Kanda M , et al. Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor...
CAS 1621673-53-7
MW: 481.67 D
From 44.00€ *
Review