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Rofecoxib
Rofecoxib

Item number: TGM-T1185-100mg

Description: Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and...
Keywords: MK 966, MK-0966
Application: Targets prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (PTGS2, COX2)
CAS 162011-90-7
MW: 314.36 D
From 40.00€ *
Review
Rofecoxib
Rofecoxib

Item number: Cay10010260-50

Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2 over COX-1 with IC50 values of 0.018 and >15 µM, respectively, for production of prostaglandin E2 (PGE2, Cay-14010) in CHO cells expressing the recombinant human enzymes. In vivo, rofecoxib inhibits carrageenan-induced paw...
Keywords: MK-966, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
Application: COX-2 inhibitor
CAS 162011-90-7
MW: 314.4 D
From 117.00€ *
Review
Rofecoxib
Rofecoxib

Item number: LKT-R5722.1

Rofecoxib is a cyclooxygenase-2 inhibitor (COX-2) that is used as an anti-inflammatory compound.
Application: COX-2 inhibitor
CAS 162011-90-7
MW: 314,36 D
From 141.00€ *
Review