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Item number: Cay43027-10

UCB 9608 is an inhibitor of PI4KIIIbeta (IC50 = 11 nM). It is selective for PI4KIIIbeta over 8 other phosphatidylinositol kinases at 10 µM. UCB 9608 inhibits the mixed lymphocyte reaction in isolated human peripheral blood mononuclear cells (PBMCs, IC50 = 37 nM). It increases heart allograft survival in mice when...

Keywords:	(3S)-4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-1-piperazinecarboxamide
Application:	PI4KIII beta (PI4KB, phosphatidylinositol 4-kinase B) inhibitor
CAS	1616413-96-7
MW:	410.48 D

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UCB9608

Item number: TGM-TQ0009-100mg

Description: UCB9608 is a selective and orally active PI4KIIIbeta inhibitor (IC50: 11 nM), selective over PI3KC2 alpha, beta, and gamma lipid kinases. Target: PI4K. Smiles: COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1. References: Reuberson J, et al. Discovery of a Potent, Orally Bioavailable...

CAS	1616413-96-7
MW:	410.47 D

From 49.00€ *

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