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Item number: Cay29514-10

Cyclo(RGDfK) is a synthetic lipopeptide inhibitor of alphavbeta3 integrin (IC50 = 1.33 nM). Osteoblast cultures, which express alphavbeta5 and alphavbeta3 integrins, but not M21L cells that do not express these integrins, bind to cyclo(RGDfK)-coated surfaces. Cyclo(RGDfK) is taken up into tumors in vivo and in vitro...

Keywords:	Cyclo(Arg-Gly-Asp-D-Phe-Lys), cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl)
Application:	alphavbeta3 integrin synthetic lipopeptide inhibitor
CAS	161552-03-0
MW:	603.7 D

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