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Item number: Cay45729-10

ARN3261 is an inhibitor of salt-inducible kinase 2 (SIK2). It induces apoptosis in OVCAR-8, SKOV3, and OC 316 ovarian cancer cells and inhibits growth in ten ovarian cancer cell lines (IC50s = 0.8-2.6 µM). ARN3261 enhances sensitivity to carboplatin (Cay13112) in both carboplatin-sensitive and -resistant ovarian...

Keywords:	GRN-300, 3-(3,5-difluoro-2-methoxyphenyl)-5-[1[1-(methylsulfonyl)-4-piperidinyl]-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine
Application:	SIK2 inhibitor
CAS	1613711-28-6
MW:	487.53 D

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