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Item number: Cay14469-5

cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and...

Keywords:	2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-4-isoxazolyl)-1-[(2S)-2-(4-morpholinyl)propyl]-1H-benzimidazole
Application:	CREBBP / EP300 bromodomain inhibitor
CAS	1613695-14-9
MW:	509 D

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SGC-CBP30

Item number: TGM-T6668-100mg

Description: SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM). Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: COc1ccc(CCc2nc3cc(ccc3n2C[C@H](C)N2CCOCC2)-c2c(C)noc2C)cc1Cl. References: Structural Genomics Consortium

Application:	CREBBP / EP300 bromodomain inhibitor
CAS	1613695-14-9
MW:	509.04 D

From 43.00€ *

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