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Item number: TGM-T4965L-10mg

Description: TCS-OX2-29 is a selective orexin-2 receptor antagonist (IC50 = 40 nM), which plays an important role in pain modulation. Target: Others. Smiles: C([C@@H](NCC=1C=CN=CC1)C(C)(C)C)(=O)N2CC=3C(=CC(OC)=C(OC)C3)CC2.Cl

Keywords:	TCS-OX229, TCS OX229, TCSOX 229, TCS OX2 29, TCSOX-229, TCSOX229
Application:	OX2R antagonist
CAS	1610882-30-8
MW:	433.97 D

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TCS-OX2-29

Item number: Cay17419-10

Orexin receptors R1 (OX1R) and OX2R mediate the action of the neuropeptides orexin A and orexin B. TCX-OX2-29 is an antagonist of OX2R (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively). It blocks the inhibitory action of orexin A on...

Keywords:	(2S)-1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone,...
Application:	OX2R antagonist
CAS	1610882-30-8
MW:	434 D

From 133.00€ *

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