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DMP-543
DMP-543

Item number: TGM-T15143-100mg

Description: DMP-543 (XR-543) is a KV7 channel blocker that enhances neurotransmitter release. Target: Others, Potassium Channel. Smiles: Fc1cc(CC2(Cc3ccnc(F)c3)c3ccccc3C(=O)c3ccccc23)ccn1. References: Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric...
Keywords: XR-543
Application: Kv7.2 inhibitor
CAS 160588-45-4
MW: 412.43 D
From 48.00€ *
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DMP 543
DMP 543

Item number: Cay32849-1

DMP 543 is an inhibitor of the voltage-gated potassium channel Kv7.2 (IC50 = 0.048 µM) and a derivative of linopirdine (Cay-19547). It enhances potassium-induced acetylcholine (ACh) release in rat hippocampal slices (EC50 = 0.83 µM). DMP 543 (1 mg/kg) increases hippocampal extracellular ACh levels in rats.Formal...
Keywords: 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone
Application: Kv7.2 inhibitor
CAS 160588-45-4
MW: 412.4 D
From 44.00€ *
Review