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Item number: Cay39835-1

GSK843 is an inhibitor of receptor-interacting serine/threonine kinase 3 (RIPK3, IC50 = 6.5 nM). It is selective for RIPK3 over a panel of 300 additional kinases at 1 µM. GSK843 (10 µM) induces apoptosis in L-929 fibroblasts. It inhibits TNF-alpha-induced necroptosis in primary human neutrophils in a...

Keywords:	3-(5-benzothiazolyl)-7-(1,3-dimethyl-thieno[3,2-c]pyridin-4-amine
Application:	RIPK3 inhibitor
CAS	1601496-05-2
MW:	377.5 D

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