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Item number: TGM-T5515-1g

Description: Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting delta-aminolevulinic acid synthetase activity through biochemical feedback. Target: Autophagy,...

Keywords:	Hemin chloride
Application:	Targets 5-aminolevulinate synthase [EC:2.3.1.37] (E2.3.1.37, ALAS)
CAS	16009-13-5
MW:	651.94 D

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Hemin chloride

Item number: Cay16487-1

Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...

Keywords:	(SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-kappaN21, kappaN22, kappaN23,...
Application:	EIF2AK1 inhibitor
CAS	16009-13-5
MW:	652 D

From 67.00€ *

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