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Item number: Cay25647-5

Tilfrinib is an inhibitor of breast tumor kinase/protein tyrosine kinase 6 (BRK/PTK6, IC50 = 3.15 nM). It is selective for BRK/PTK6 over HER2 (IC50 = 1,300 nM). Tilfrinib inhibits the growth of MCF-7, HS-578/T, and BT-549 breast cancer cells in vitro (GI50s = 0.99, 1.02, and 1.58 µM, respectively).Formal Name:...

Keywords:	3-(9H-pyrido[2,3-b]indol-4-ylamino)-phenol
Application:	BRK / PTK6 inhibitor
CAS	1600515-49-8
MW:	275.3 D

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Tilfrinib

Item number: TGM-T17098-5mg

Description: Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities. Target: BTK. Smiles: Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1. References: Mahmoud KA, et al. Discovery of 4-anilino alpha-carbolines as novel Brk...

Application:	BRK / PTK6 inhibitor
CAS	1600515-49-8
MW:	275.3 D

From 37.00€ *

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