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Item number: Cay18792-5

Epstein-Barr virus-induced G protein-coupled receptor 2 (EBI2, also known as GPR183) is an oxysterol receptor involved in B cell migration and function. NIBR189 is an antagonist of EBI2 (IC50s = 11 and 15 nM for human and mouse receptors, respectively). It is selective for EBI2 over a panel of other receptors,...

Keywords:	3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2E-propen-1-one
Application:	EBI2 / GPR183 antagonist
CAS	1599432-08-2
MW:	429.3 D

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NIBR189

Item number: TGM-T7156-100mg

Description: NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively). Target: EBI2/GPR183. Smiles: COc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Br)cc1. References: Gessier F , Preuss I , Yin H , et al. Identification and...

Application:	EBI2 / GPR183 antagonist
CAS	1599432-08-2
MW:	429.31 D

From 30.00€ *

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