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MC-Val-Cit-PABC-PNP
MC-Val-Cit-PABC-PNP

Item number: TGM-T3503-50mg

Description: MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage...
Keywords: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
CAS 159857-81-5
MW: 737.76 D
30.00€ *
Review
Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP

Item number: Cay23881-1

Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin (Cay-15007) or...
Keywords: Maleimidocaproyl-L-Valine-L-Citrulline-p-Aminobenzyl Alcohol p-Nitrophenyl Carbonate,...
Application: Peptide linker, antibody-drug conjugate synthesis
CAS 159857-81-5
MW: 737.8 D
From 44.00€ *
Review