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Item number: Cay34818-100

Val-Cit-PAB-OH is a peptide linker molecule used in the synthesis of drug conjugates. It is cleaved by cathepsin B, a protease highly expressed in cancer cells, which confers specificity of the drug conjugates to cancer cells. Val-Cit-PAB-OH has been used in the synthesis of antibody-drug conjugates (ADCs)...

Keywords:	Valine-Citrulline-p-Aminobenzylcarbamate, VC-PAB, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
Application:	Peptide linker molecule, Cathepsin B substrate
CAS	159857-79-1
MW:	379.5 D

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