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trans-ISRIB
trans-ISRIB

Item number: Cay16258-5

Phosphorylation of eIF2alpha by several kinases in response to cellular stress, including accumulation of unfolded proteins in the ER, results in a decrease in overall protein synthesis but upregulation of a small number of key regulatory proteins. trans-ISRIB (Integrated Stress Response Inhibitor) is a symmetric...
Keywords: N,N'-((1r,4r)-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)
Application: EIF2AK3 / PERK inhibitor
CAS 1597403-47-8
MW: 451.3 D
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