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CW069
Item number: Cay22936-1
CW069 is an allosteric inhibitor of KIFC/HSET (IC50 = 75 µM), a microtubule motor protein involved in bipolar spindle assembly and centrosome clustering. It increases the number of multipolar spindles in N1E-115 mouse neuroblastoma cells with supernumerary centrosomes when used at concentrations of 100 and 200 µM,...
| Keywords: | 5-iodo-2-[[(2S)-1-oxo-3-phenyl-2-[(phenylmethyl)amino]propyl]amino]-benzoic acid |
| Application: | Allosteric HSET inhibitor |
| CAS | 1594094-64-0 |
| MW: | 500.3 D |
From 89.00€
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CW-069
Item number: TGM-T6209-100mg
Description: CW-069 (IC50=75 µM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP. Target: Kinesin, Microtubule Associated. Smiles: OC(=O)c1cc(I)ccc1NC(=O)[C@H](Cc1ccccc1)NCc1ccccc1. References: Watts CA, et al. Chem Biol. 2013, 20(11), 1399-1410.
| Keywords: | CW069 |
| Application: | Allosteric HSET inhibitor |
| CAS | 1594094-64-0 |
| MW: | 500.33 D |
From 35.00€
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