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L755507
Item number: TGM-T6872-100mg
Description: L755507 is an effective, selective agonist of beta3-AR(IC50=35 nM). Target: CRISPR/Cas9, Adrenergic Receptor. Smiles: CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1. References: Parmee ER, et al. Bioorg Med Chem Lett. 1998, 8(9):1107-1112.
| Application: | Partial beta-3 adrenergic receptor agonist |
| CAS | 159182-43-1 |
| MW: | 584.73 D |
From 45.00€
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L-755,507
Item number: Cay18629-1
L-755,507 is a partial agonist of beta3-adrenergic receptors (EC50 = 0.43 nM). It displays more than 440-fold selectivity for beta3- over beta1- and beta2-adrenoceptors (EC50s = 580 and >10,000 nM, respectively). At 5 µM, this compound has been used to enhance CRISPR-mediated homology-directed repair efficiency by...
| Keywords: | 4-[[(hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamide |
| Application: | Partial beta-3 adrenergic receptor agonist |
| CAS | 159182-43-1 |
| MW: | 584.7 D |
From 44.00€
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