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Cariporide
Item number: Cay16935-5
Cariporide is an inhibitor of sodium-hydrogen exchanger 1 (NHE-1, IC50 = 0.56 µM in an intracellular pH recovery assay). It is selective for NHE-1 over NHE-2 (IC50 = 28 µM in an intracellular pH recovery assay). Cariporide inhibits sodium propionate-induced swelling of isolated human platelets (IC50 = 0.023 µM). It...
| Keywords: | HOE 642, N-(aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide |
| Application: | NHE-1 inhibitor |
| CAS | 159138-80-4 |
| MW: | 283.3 D |
From 97.00€
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Cariporide
Item number: TGM-T2238-5mg
Description: Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1). Target: Sodium Channel. Smiles: CC(C)c1ccc(cc1S(C)(=O)=O)C(=O)N=C(N)N....
| Keywords: | HOE-642 |
| Application: | NHE-1 inhibitor |
| CAS | 159138-80-4 |
| MW: | 283.35 D |
From 38.00€
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