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Item number: Cay32774-1

GR159897 is a nonpeptide antagonist of the neurokinin-2 (NK2) receptor. It binds to NK2 receptors (Ki = 0.32 nM) and is selective for NK2 over NK1 and NK3 receptors in radioligand binding assays (Kis = 5,010 and >1,000 nM, respectively). GR159897 inhibits contractions induced by the NK2 receptor agonist GR64349 in...

Keywords:	5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole
Application:	Nonpeptide NK2 receptor antagonist
CAS	158848-32-9
MW:	414.5 D

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