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Perifosine
Item number: Cay10008112-1
Alkylphospholipids are a class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine is an alkylphospholipid that induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent...
| Keywords: | 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethyl-piperidinium, inner salt |
| Application: | Antineoplastic, apoptosis inducer |
| CAS | 157716-52-4 |
| MW: | 461.7 D |
From 56.00€
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Perifosine
Item number: LKT-P1969.1
Perifosine is an alkylphospholipid analog that exhibits anticancer chemotherapeutic and anti-inflammatory activities. Perifosine directly inhibits Akt by binding at multiple sites. In macrophages, perifosine inhibits LPS-induced increases in TNF- and ERK activation and activates AMPK. In colorectal cancer,...
| Application: | Antineoplastic, Apoptosis inducer |
| CAS | 157716-52-4 |
| MW: | 461.66 D |
From 146.00€
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Perifosine
Item number: TGM-T2492-100mg
Description: Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity. Target: Autophagy, Apoptosis, Akt. Smiles: O(P(OCCCCCCCCC CCCCCCCCC)(=O)[O-])C1CC[N+](C)(C)CC1. References: Vyomesh Patel, et al. Cancer Res, 2002, 62(5), 1401-1409
| Keywords: | D21266, KRX-0401, NSC 639966 |
| CAS | 157716-52-4 |
| MW: | 461.66 D |
From 38.00€
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