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CPUY192018

Item number: Cay45473-10

An inhibitor of the Keap1-Nrf2 protein-protein interaction (IC50 = 28.5 nM in a TR-FRET assay), induces Nrf2-mediated transcriptional activity in a reporter assay using HepG2 cells, prevents DSS-induced apoptosis and S-phase cell cycle arrest and reduces DSS-induced increases in ROS levels in NCM460 cells at 10 µM,...

Keywords:	N,N'-1,4-naphthalenediylbis[N-[(4-methoxyphenyl)sulfonyl]-glycine
Application:	Keap1-Nrf2 protein-protein interaction inhibitor
CAS	1567836-15-0
MW:	614.64 D

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