2 products were found matching "1562993-37-6"!
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Ponatinib-d8
Item number: TGM-T12521-1mg
Description: Ponatinib D8 is a deuterium labeled Ponatinib. Ponatinib is an orally active inhibitor of multi-targeted kinase(Abl, PDGFRalpha, VEGFR2, FGFR1, and Src with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM, respectively). Smiles:...
| Keywords: | AP24534 D8 |
| Application: | GC-MS, LC-MS, internal standard, quantification, Bcr-Abl tyrosine kinase inhibitor |
| CAS | 1562993-37-6 |
| MW: | 540.61 D |
From 276.00€
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Ponatinib-d8
Item number: Cay28905-1
Ponatinib-d8 is intended for use as an internal standard for the quantification of ponatinib (Cay-11494) by GC- or LC-MS. Ponatinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor (IC50 = 0.37 nM). It inhibits the tyrosine kinase inhibitor-resistant mutant Bcr-AblT315I (IC50 = 2 nM), as well as...
| Keywords: | 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-3-(trifluorome... |
| Application: | GC-MS, LC-MS, internal standard, quantification, Bcr-Abl tyrosine kinase inhibitor |
| CAS | 1562993-37-6 |
| MW: | 540.6 D |
484.00€
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