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Ibrutinib-d5
Item number: Cay22561-1
Ibrutinib-d5 is intended for use as an internal standard for the quantification of ibrutinib (Cay-16274) by GC- or LC-MS. Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 0.5 nM) that selectively blocks B cell activation, promoting apoptosis and preventing homing to the protective...
| Keywords: | 1-[(3R)-3-[4-amino-3-[4-(phenoxy-2,3,4,5,6-d5)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one |
| Application: | GC-MS, LC-MS, internal standard, BTK inhibitor |
| CAS | 1553977-17-5 |
| MW: | 445.5 D |
From 206.00€
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Ibrutinib-d5
Item number: TGM-T11601-10mg
Description: Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor. Smiles: [2H]c1c([2H])c([2H])c(Oc2ccc(cc2)-c2nn([C@@H]3CCCN(C3)C(=O)C=C)c3ncnc(N)c23)c([2H])c1[2H]. References: Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is...
| Keywords: | Ibrutinib D5, PCI-32765 D5 |
| CAS | 1553977-17-5 |
| MW: | 445.53 D |
From 280.00€
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