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Item number: Cay27647-1

CHM-1 is an inhibitor of tubulin polymerization (IC50 = 0.68 µM) with anticancer activity. It inhibits colchicine (Cay-9000760) tubulin binding by 39% when used at a concentration of 5 µM. CHM-1 inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 =...

Keywords:	NSC 656158, 6-(2-fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one
Application:	Tubulin polymerization inhibitor
CAS	154554-41-3
MW:	283.3 D

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CHM-1

Item number: TGM-T22661-100mg

Description: CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo. Target: Others, Apoptosis, Microtubule Associated. Smiles:...

CAS	154554-41-3
MW:	283.25 D

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