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6-Thioguanine
Item number: TGM-T3089-100mg
Description: 6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia. Target: Endogenous Metabolite, DNA Methyltransferase, DUB, SARS-CoV, Autophagy, Apoptosis. Smiles: NC1=NC2=C(N=CN2)C(S)=N1. References:...
| Keywords: | Thioguanine, 2-Amino-6-mercaptopurine, 6-TG, 2-Amino-6-purinethiol |
| Application: | Targets hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] (hprT, hpt, HPRT1) |
| CAS | 154-42-7 |
| MW: | 167.19 D |
From 42.00€
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6-Thioguanine
Item number: Cay15774-250
6-Thioguanine (6-TG) is a thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity. Upon incorporation into DNA, 6-TG has been shown to disrupt cytosine methylation by DNA methyltransferases,...
| Keywords: | 6-TG, NSC 752, NSC 76504, 2-amino-1,9-dihydro-6H-purine-6-thione |
| Application: | Double-strand break inducer |
| CAS | 154-42-7 |
| MW: | 167.2 D |
From 44.00€
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6-Thioguanine
Item number: LKT-T2835.1
Nucleotide (guanine) analog, prevents guanine synthesis, DNA replication inhibitor.
| Keywords: | tioguanine, thioguanine |
| Application: | Cancer studies |
| CAS | 154-42-7 |
| MW: | 167,19 D |
From 110.00€
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Thioguanine
Item number: ISO-S13341-1.0
| Keywords: | unlabelled |
| CAS | 154-42-7 |
| MW: | 167 D |
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