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Item number: Cay18405-1

Fibroblast growth factor receptor 4 (FGFR4) is the receptor for fibroblast growth factor 19 (FGF19), which is a tightly controlled hormone that regulates bile acid synthesis and hepatocyte proliferation in the normal liver. Aberrant signaling through the FGFR4/FGF19 signaling complex has been implicated in...

Keywords:	N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-2-propenamide
Application:	FGFR4 inhibitor
CAS	1538604-68-0
MW:	509.4 D

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BLU9931

Item number: TGM-T2347-100mg

Description: BLU9931 is the first selective small molecule inhibitor of FGFR4. Target: FGFR. Smiles: COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(Nc3c(C)cccc3NC(=O)C=C)ncc2c1. References: Hagel M, et al. Cancer Discov. 2015, 5(4), 424-437.

CAS	1538604-68-0
MW:	509.38 D

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