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Item number: Cay32845-1

Gavestinel is an NMDA receptor antagonist. It selectively binds to the glycine site of the NMDA receptor over the glutamate binding site of NMDA, AMPA, or ionotropic kainate (GluK) receptors (Kis = 0.003, 10, 7.94, and 3.98 µM, respectively) and is selective for the NMDA receptor over a panel of 70 receptors (IC50s...

Keywords:	GV150526A, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-1H-indole-2-carboxylic acid, monosodium salt
Application:	NMDA receptor antagonist
CAS	153436-38-5
MW:	397.2 D

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Gavestinel sodium

Item number: TGM-T22798-100mg

Description: Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.Gavestinel binds to the glycine site of the NMDA receptor with a binding affinity (pKi value) of 8.5.Gavestinel is used in acute ischaemic stroke studies. Target: NMDAR, iGluR. Smiles:...

Keywords:	Gavestinel sodium salt, GV 150526
CAS	153436-38-5
MW:	397.19 D

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