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ML-355
ML-355

Item number: Cay18537-1

Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
Keywords: N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-benzenesulfonamide
Application: 12-LO inhibitor
CAS 1532593-30-8
MW: 441.5 D
From 73.00€ *
Review
ML355
ML355

Item number: TGM-T4347-1mg

Description: ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 µM), possess favorable ADME properties. Target: Lipoxygenase. Smiles: COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nc3ccccc3s2)c1O. References: Zhang XJ, et al. An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic...
Application: 12-LO inhibitor
CAS 1532593-30-8
MW: 441.52 D
From 37.00€ *
Review