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AB-MECA
Item number: TGM-T14082-10mg
Description: AB-MECA is a high-affinity A3 adenosine receptor agonist with significant affinity for recombinant A1 and A3 receptors. Target: Others. Smiles: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccc(N)cc3)ncnc12. References: Shearman LP, et al. [125I]4-aminobenzyl-5'-N-methylcarboxamidoadenosine...
| Application: | Adenosine receptor A3 agonist |
| CAS | 152918-26-8 |
| MW: | 399.4 D |
From 181.00€
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AB-MECA
Item number: Cay28415-1
AB-MECA is an adenosine A3 receptor agonist (Ki = 430.5 nM for the human receptor expressed in CHO cells). It inhibits LPS-induced TNF-alpha production in primary cultured human lung macrophages (pD2 = 6.9). AB-MECA increases contraction of isolated guinea pig trachea ex vivo when used at a concentration of 0.1 µM...
| Keywords: | 1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-beta-D-ribofuranuronamide |
| Application: | Adenosine receptor A3 agonist |
| CAS | 152918-26-8 |
| MW: | 399.4 D |
From 100.00€
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