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A-366
Item number: Cay16081-5
A-366 is a potent, peptide-competitive inhibitor of the lysine methyltransferase G9a (IC50 = 3.3 nM). It displays greater than 1,000-fold selectivity over 21 other methyltransferases. A-366 significantly reduces the cellular levels of dimethylation on histone 3 at lysine 9 (H3K9Me2) in PC3 cells without reducing...
| Keywords: | 5'-methoxy-6'-[3-(1-pyrrolidinyl)propoxy]-spiro[cyclobutane-1,3'-[3H]indol]-2'-amine |
| Application: | EHMT2 inhibitor |
| CAS | 1527503-11-2 |
| MW: | 329.4 D |
From 127.00€
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A-366
Item number: TGM-T3624-100mg
Description: A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 methyltransferases. It is an inhibitor of the Spindlin1-H3K4me3 interaction with an...
| Keywords: | A366, A 366 |
| Application: | EHMT2 inhibitor |
| CAS | 1527503-11-2 |
| MW: | 329.44 D |
From 30.00€
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