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SB-204741
Item number: Cay32965-50
SB-204741 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT2B. It inhibits 5-HT-induced contraction of isolated rat stomach fundus, a tissue that endogenously expresses high levels of 5-HT2B receptors (pA2 = 7.95). SB-204741 is selective for 5-HT2B receptors over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C,...
| Keywords: | N-(1-methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)-urea |
| Application: | 5-HT2B receptor antagonist |
| CAS | 152239-46-8 |
| MW: | 286.4 D |
From 106.00€
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SB 204741
Item number: TGM-T23312-100mg
Description: SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1. Target: 5-HT Receptor. Smiles: Cc1cc(NC(=O)Nc2ccc3n(C)ccc3c2)sn1. References: Ozdemir E, Demirkazik A, Taskiran AS, Arslan G. Effects of 5-HT1 and 5-HT 2 Receptor Agonists on Electromagnetic Field-Induced Analgesia in...
| Application: | 5-HT2B receptor antagonist |
| CAS | 152239-46-8 |
| MW: | 286.35 D |
From 34.00€
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