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XEN445
XEN445

Item number: Cay19144-1

Endothelial lipase, a member of the triglyceride lipase gene family expressed in endothelial cells, prefers phospholipid-enriched high-density lipoprotein (HDL) over triglyceride as a substrate. XEN445 is an endothelial lipase inhibitor (IC50 = 237 nM) that demonstrates selectivity for endothelial lipase compared to...
Keywords: 2-[(3S)-3-(2-pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)-benzoic acid
Application: Endothelial lipase inhibitor
CAS 1515856-92-4
MW: 366.3 D
From 49.00€ *
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XEN445
XEN445

Item number: TGM-T2249-100mg

Description: XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties. Target: Lipase, Others. Smiles: OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F
Keywords: XEN 445 , XEN-445
Application: Endothelial lipase inhibitor
CAS 1515856-92-4
MW: 366.33 D
From 32.00€ *
Review