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1-Aminodecylidene bis-Phosphonic Acid
Item number: Cay13583-1
1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 µM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone (Cay-11015) in HepG2 cells.Formal...
| Keywords: | 1-Amindecane-1,1-Diphosphonic Acid, ARC 39, (1-aminodecane-1,1-diyl)diphosphonic acid, monosodium salt |
| Application: | Acid sphingomyelinase inhibitor |
| CAS | 15049-93-1 |
| MW: | 317.3 D |
From 144.00€
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1-Aminodecylidene bis-Phosphonic Acid
Item number: TGM-T84472-10mg
Description: 1-Aminodecylidenebis-phosphonic acid, with its potent inhibitory effect on acid sphingomyelinase (IC50= 20 nM), shows selectivity by being less effective against neutral sphingomyelinase (IC50= >100 µM). Additionally, it entirely prevents dexamethasone-induced apoptosis in HepG2 cells. Target: Others....
| Keywords: | 1-Amindecane-1,1-Diphosphonic Acid |
| Application: | Acid sphingomyelinase inhibitor |
| CAS | 15049-93-1 |
| MW: | 317.26 D |
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