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Item number: Cay26126-1

Asciminib is an allosteric inhibitor of Abl1 (IC50 = 0.45 nM). It is selective for Abl1 over a panel of more than 60 additional kinases (IC50s = >10 µM), as well as ion channels, nuclear receptors, G protein-coupled receptors (GPCRs), and transporters. Asciminib inhibits the proliferation of Luc-Ba/F3 cells...

Keywords:	ABL001, N-[4-(chlorodifluoromethoxy)phenyl]-6-[(3R)-3-hydroxy-1-pyrrolidinyl]-5-(1H-pyrazol-3-yl)-3-pyridinecarboxamide
Application:	Allosteric Abl1 inhibitor
CAS	1492952-76-7
MW:	449.8 D

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