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Item number: TGM-T41247-10mg

Description: Thioperamide maleate (MR-12842 maleate) is an effective and selective H3 receptor antagonist (Ki = 4.3 nM) that inhibits [3H]histamine synthesis (Ki = 31 nM). Target: Histamine Receptor. Smiles: OC(=O)\C=C/C(O)=O.S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1. References: Na Wang, et al. Histamine H3 Receptor...

Keywords:	MR-12842 maleate
Application:	Histamine H3 receptor antagonist
CAS	148440-81-7
MW:	408.52 D

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Thioperamide (maleate)

Item number: Cay10011127-1

Thioperamide (maleate) is a selective histamine H3 receptor antagonist that crosses the blood-brain barrier. This compound binds to rat cerebral cortical cells in vitro with a pKi value of 8.4 and inhibits histamine binding in vivo with an ED50 value of 1 mg/kg. At a dose of 5 mg/kg thioperamide (maleate) inhibits...

Keywords:	N-cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide, 2Z-butenedioate
Application:	Histamine H3 receptor antagonist
CAS	148440-81-7
MW:	408.5 D

From 21.00€ *

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