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Item number: Cay23497-1

BMS 986120 is an orally bioavailable, selective, and reversible antagonist of proteinase-activated receptor 4 (PAR4, IC50 = 0.56 nM to inhibit calcium mobilization induced by PAR4 agonist peptide (PAR4-AP) in HEK293 cells). It is selective for PAR4 over PAR1, PAR2, and a panel of purified proteases, including...

Keywords:	2-methoxy-6-[6-methoxy-4-[[5-methyl-2-(4-morpholinyl)-4-thiazolyl]methoxy]-2-benzofuranyl]-imidazo[2,1-b]-1,3,4-thiadiazole
Application:	Proteinase-activated receptor 4 (PAR-4) antagonist
CAS	1478712-37-6
MW:	513.6 D

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BMS-986120

Item number: TGM-T14684-100mg

Description: BMS-986120 is a first-in-class oral, reversible protease-activated receptor 4 (PAR4) antagonist with IC50s of 9.5 nM in human blood and 2.1 nM in monkey blood, exhibiting potent and selective antiplatelet effects[1][2]. Target: Others. Smiles: COc1nn2cc(nc2s1)-c1cc2c(OCc3nc(sc3C)N3CCOCC3)cc(OC)cc2o1....

Application:	Proteinase-activated receptor 4 (PAR-4) antagonist
CAS	1478712-37-6
MW:	513.59 D

From 1,023.00€ *

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