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Item number: Cay29704-10

8-(3-Chlorostyryl)caffeine (CSC) is an adenosine A2 receptor antagonist (Ki = 54 nM). It is selective for adenosine A2 over A1 receptors (Ki = 28 µM). CSC reverses locomotor depression induced by the adenosine A2A agonist APEC in mice (ED50 = 16 µg/kg, i.p.). It increases locomotion in mice when administered at a...

Keywords:	CSC, 8-[(1E)-2-(3-chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Application:	Adenosine A2 receptor antagonist
CAS	147700-11-6
MW:	330.8 D

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