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Item number: Cay14018-250

WIN 18,446 is a bis-(dichloroacetyl)-diamine which inhibits aldehyde dehydrogenase 1a2, (IC50 = 300 nM), a testes-specific isoform of the enzyme involved in vitamin A metabolism. In this way, WIN 18,446 suppresses the expression of several genes that are regulated by retinoic acid and are necessary for...

Keywords:	NSC 59354, N,N'-1,8-octanediylbis[2,2-dichloro-acetamide]
CAS	1477-57-2
MW:	366.1 D

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