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Item number: TGM-T6264-100mg

Description: Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and...

Keywords:	Actelion, Benzenesulfonamide, Ro 47-0203
Application:	Antihypertensive, Endothelin receptor antagonist
CAS	147536-97-8
MW:	551.614 D

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Bosentan

Item number: Cay11731-10

Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM).Formal Name: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide. CAS Number: 147536-97-8. Synonyms: Ro 47-0203. Molecular Formula: C27H29N5O6S. Formula Weight:...

Keywords:	Ro 47-0203, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide
Application:	Endothelin receptor antagonist
CAS	147536-97-8
MW:	551.6 D

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