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KT185
Item number: TGM-T15668-10mg
Description: KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells). Target: Others. Smiles: O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1. References: Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective,...
| Application: | ABHD6 inhibitor |
| CAS | 1472640-86-0 |
| MW: | 519.64 D |
From 233.00€
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KT185
Item number: Cay19113-10
KT185 is an orally bioavailable inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 0.21 nM in a competitive activity-based protein profiling assay using Neuro2A membranes. It inhibits ABHD6 in a 2-arachidonoyl glycerol (2-AG, Cay-62160) hydrolysis assay (IC50 = 13.6 nM for...
| Keywords: | [4'-[1-[(2-phenyl-1-piperidinyl)carbonyl]-1H-1,2,3-triazol-4-yl][1,1'-biphenyl]-3-yl]-1-piperidinyl-methanone |
| Application: | ABHD6 inhibitor |
| CAS | 1472640-86-0 |
| MW: | 519.6 D |
From 128.00€
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