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Cytarabine
Cytarabine

Item number: Cay16069-10

Cytarabine (ara-C) is a nucleoside analog and prodrug form of the DNA polymerase inhibitor ara-CTP. It is triphosphorylated to ara-CTP by the successive actions of deoxycytidine kinase, deoxycytidylate kinase, and nucleoside diphosphate kinase. Ara-C inhibits proliferation of HL-60, ML-1, Raji, and Jurkat human...
Keywords: 1-beta-D-Arabinofuranosylcytosine, NSC 287459, NSC 63878, U-19920A, 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
Application: Competitive DNA polymerase inhibitor
CAS 147-94-4
MW: 243.2 D
From 66.00€ *
Review
Cytarabine
Cytarabine

Item number: LKT-C9778.1

Cytarabine is an antimetabolite compound which is proven to be one of the most effective agents available to treat leukemia. It induces its cytotoxic effect by inactivating DNA polymerases alpha, delta, and epsilon and consequently inhibit semi-conservative DNA replication and repair. It also has a potential to...
Keywords: Ara-C, Arabinofuranosyl Cytidine, cytosine arabinoside
Application: DNA replication inhibitor
CAS 147-94-4
MW: 243,22 D
From 69.00€ *
Review