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Item number: Cay38416-1

PF-249 is an allosteric activator of AMP-activated protein kinase beta1 (AMPKbeta1) heterotrimers (EC50s = 8 and 6 nM for human AMPK alpha1beta1gamma1 and -alpha2beta1gamma1, respectively). It is selective for AMPK alpha1beta1gamma1 and -alpha2beta1gamma1 over AMPK alpha1beta2gamma1, -alpha2beta2gamma1, and...

Keywords:	PF-06885249, 6-chloro-5-[6-(dimethylamino)-2-methoxy-3-pyridinyl]-1H-indole-3-carboxylic acid
Application:	Allosteric AMPKbeta1 heterotrimer activator
CAS	1467059-70-6
MW:	345.8 D

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PF-249

Item number: TGM-T24626-100mg

Description: PF-249 (PF-06685249) is a beta1-selective AMPK with an EC50 of 12 nM for AMPK alpha1beta1gamma1 and can be used in studies about diabetic nephropathy. Target: AMPK. Smiles: COc1nc(ccc1-c1cc2c(c[nH]c2cc1Cl)C(O)=O)N(C)C

Keywords:	PF-06685249 , PF 06685249 , PF06685249
Application:	Allosteric AMPKbeta1 heterotrimer activator
CAS	1467059-70-6
MW:	345.78 D

From 39.00€ *

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