2 products were found matching "1467057-23-3"!

No results were found for the filter!

Item number: Cay27366-1

PF-06409577 is an activator of AMP-activated protein kinase (AMPK) heterotrimers (Kd = 9 nM for alpha1beta1gamma1). In vitro, it selectively activates beta1-containing AMPK isoforms (EC50s = 2.18-7.03 nM) over beta2-containing isoforms (EC50s = >10 µM). PF-06409577 has an EC50 value of 7 nM in an...

Keywords:	6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
Application:	AMPK heterotrimer activator
CAS	1467057-23-3
MW:	341.8 D

From 49.00€ *

Show details

Review

PF-06409577

Item number: TGM-T4427-100mg

Description: PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for alpha1beta1gamma1). Target: AMPK. Smiles: OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)C1(O)CCC1. References: Cameron K O, Kung D W, Kalgutkar A S, et al. Discovery and preClinicalal characterization of...

Keywords:	PF 06409577
Application:	AMPK heterotrimer activator
CAS	1467057-23-3
MW:	341.79 D

From 37.00€ *

Show details

Review

Didn't find the right Product? Here are some useful Search Tips!

Checklist-Thumbnail

All our products have English titles and descriptions. Therefore, use English search terms.
Write out Greek letters - i.e. "alpha" instead of α or "beta" instead of β.
Do not add "and" when entering multiple search terms.
Use the singular (e.g. "antibody" instead of "antibodies").
If available, try synonyms (e.g. for a specific protein).
You can search for chemical substances using the unique CAS number (Chemical Abstracts Service).
In addition, you can also use the UniProt or KEGG accession number for the product search.
Use our filter function to narrow down your search results. If you want to remove a selected filter again, click on the small "x" next to the filter.
Are you looking for products from a specific supplier? Then enter the corresponding supplier name and select it in the appearing suggestion field. Alternatively, you can also use our supplier overview.
Use - if known - the specific product number. Especially for short numbers, note the supplier code in front of each number for most of our partners (e.g. for AAT Bioquest "ABD-121" instead of just "121"). Click on the button below to find all supplier codes and additional information.

All Supplier Codes

We would be very happy to support you in your product search! Contact us at info@biomol.com.