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Item number: TGM-T11032-10mg

Description: DHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. As an amino acid, it serves as a selective and potent agonist for Group I mGluR (mGluR 1 and mGluR 5) without affecting Group II or Group III mGluRs. Target: GluR. Smiles: Cl.NC(C(O)=O)c1cc(O)cc(O)c1. References: Winder...

Keywords:	(RS)-3,5-DHPG
CAS	146255-66-5
MW:	183.16 D

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(R,S)-3,5-DHPG

Item number: Cay35912-10

(R,S)-3,5-DHPG is an agonist of group I metabotropic glutamate receptors (mGluRs). It induces phosphoinositol hydrolysis in MCB3901, also known as AV12-664, cells expressing human mGluR1a and mGluR5a in a concentration-dependent manner. (R,S)-3,5-DHPG (10 µM) potentiates NMDA-induced depolarizations in rat...

Keywords:	(R,S)-3,5-Dihydroxyphenylglycine, DL-3,5-Dihydroxyphenylglycine, alpha-amino-3,5-dihydroxy-benzeneacetic acid
Application:	mGluR1 / mGluR5 agonist
CAS	146255-66-5
MW:	183.2 D

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