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PFK158
Item number: Cay22987-5
PFK158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, IC50 = 137 nM for human recombinant PFKFB3). It inhibits PFKFB3 and glycolysis in Jurkat cells (IC50s = 1.6 and 0.847 µM, respectively). PFK158 inhibits the growth of leukemia cells in vitro (IC50 = 0.33 µM for Jurkat cells)...
| Keywords: | 1-(4-pyridinyl)-3-[7-(trifluoromethyl)-2E-quinolinyl]-2-propen-1-one |
| Application: | PFKFB3 inhibitor |
| CAS | 1462249-75-7 |
| MW: | 328.3 D |
From 85.00€
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PFK-158
Item number: TGM-T3105-100mg
Description: PFK-158 is an effective and specific inhibitor PFKFB3. Target: Apoptosis, Glucokinase, Autophagy. Smiles: FC(F)(F)c1ccc2ccc(\C=C\C(=O)c3ccncc3)nc2c1. References: Rebecca Redman, et al. Y Res August 1, 2015 75, CT206.
| Application: | PFKFB3 inhibitor |
| CAS | 1462249-75-7 |
| MW: | 328.29 D |
From 30.00€
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