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Item number: Cay71748-10

MSDC-0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. It inactivates the mitochondrial pyruvate carrier (MPC, IC50 = 1.2 µM) without affecting peroxisome proliferator-activated receptor gamma (PPARgamma, IC50 = 31.65 µM) in vitro. MSDC-0160 enhances the rate of insulin-stimulated...

Keywords:	5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione
Application:	PPARgamma agonist
CAS	146062-49-9
MW:	370.4 D

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MSDC 0160

Item number: TGM-T2607-100mg

Description: MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease. Target: IGF-1R, Mitochondrial Metabolism, Others. Smiles: CCc1ccc(nc1)C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1. References: Rohatgi N, et al. PLoS One....

Keywords:	MSDC0160, MSDC-0160, Mitoglitazone, CAY10415
Application:	PPARgamma agonist
CAS	146062-49-9
MW:	370.42 D

From 30.00€ *

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